Prof. Dr. rer. nat. Andreas Bausch

Courses and Dates

Offered Bachelor’s or Master’s Theses Topics

Force sensor analysis by Fluroescence Lifte Time Imaging (FLIM)

The goal of this thesis is to establish a novel method to determine intracellular forces. Using fluroecently tagged proteins, Förster Energy transfer will be used to determine the changes of local strains within epethelial layers. Confocal microscopy and digital imaging processing and analysis will be employed to understand how mechanical forces lead to structure formation processes in organ- morphogenesis.

suitable as

• Bachelor’s Thesis Physics

Supervisor: Andreas Bausch

KI and Machine Learning tools to analyze organogenesis.

Recent progress enabled to build organs in the cell culture. the so called organoids are promising model systems to understand not only the physical basis of organogenesis but also have the potential to revolutionize drug development efforts. The complexity of the structure forming process requires the deployment of machine learning tools. These are already ideally suited to recognize and classify the evolving structures, in the next step we aim to push the KI based methods further - to be able to predict the developmental phases. Within this thesis the KI methods will be developed and applied to high throughput microscopy data sets.

suitable as

• Bachelor’s Thesis Physics

Supervisor: Andreas Bausch

Pattern formation in reconstituted systems

In a bottom up approach we aim to reconstructed functional modules mimicking processes found in living cells. in the Thesis pattern forming system will be combined with adhesions processes to approach the emergence of basic aspects of multicellular nature of tissues.

suitable as

• Bachelor’s Thesis Physics

Supervisor: Andreas Bausch