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Mit 1.10.2022 ist die Fakultät für Physik in der TUM School of Natural Sciences mit der Webseite https://www.nat.tum.de/ aufgegangen. Unter Umstellung der bisherigen Webauftritte finden Sie weitere Informationen.

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Prof. Dr. rer. nat. Karen Alim

Photo von Prof. Dr. rer. nat. Karen Alim.
Telefon
+49 89 289-12192
Raum
036
E-Mail
k.alim@tum.de
frauenbeauftragte@ph.tum.de (Frauenbeauftragte des Physik-Departments)
Links
Homepage
Visitenkarte in TUMonline
Arbeitsgruppe
Theorie biologischer Netzwerke
Funktionen

Lehrveranstaltungen und Termine

Titel und Modulzuordnung
ArtSWSDozent(en)Termine
From Biofluids to Bionic
eLearning-Kurs
Zuordnung zu Modulen:
VO 2 Alim, K. Mo, 14:00–16:00, CPA EG.006A
Aktuelle Entwicklungen zur Physik biologischer Netzwerke
Zuordnung zu Modulen:
PS 2 Alim, K. Mi, 10:00–12:00, virtuell
Physics & Life
Zuordnung zu Modulen:
HS 2 Alim, K. einzelne oder verschobene Termine
Seminar to From Biofluids to Bionic
Zuordnung zu Modulen:
HS 2 Alim, K.
Mentoring-Programm im Bachelorstudiengang Physik
Zuordnung zu Modulen:
KO 0.2 Alim, K. Termine in Gruppen
Repetitorium zu Physik & Leben
Zuordnung zu Modulen:
RE 2
Leitung/Koordination: Alim, K.
Revision Course to Seminar to From Biofluids to Bionic
Zuordnung zu Modulen:
RE 2
Leitung/Koordination: Alim, K.

Ausgeschriebene Angebote für Abschlussarbeiten

Active response by adaptation of mechanical properties?

The complex behavior of the giant cell Physarum polycephalum finds its origin in the versatile transformation of liquid cytoplasm to gel-like actin-myosin meshwork making up the tube walls and vice versa. These active mechanics allow the organism to recycle its’ gel-like tubes at its rear and move it in its fluid form to the front, where it grows. Also, responding to stimuli like food, touch, or light, a change in cytoplasm viscosity seems to initiate the response. Yet, what are the mechanical properties of the liquid cytoplasm, and how much do they change upon stimulation? Do the mechanical properties of the cytoplasm change with the location in the cell? The measure of the mechanical properties of cells is challenging, but one can probe their visco-elasticity by tracking injected micron-sized beads - a technique called microrheology. You will measure the mechanical properties of cytoplasm extracts and grown Physarum, and quantify how they change upon stimulation by passive and active microrheology. Task 1: Establish cytoplasm extraction following previous work in the literature. Task 2: Perform passive microrheology on cytoplasmic droplets without and with stimulation (light, food, drugs) and analyze your data quantitatively. Task 3: Establish active microrheology to extract cytoplasm viscosity in different parts of Physarum’s network.

geeignet als
  • Bachelorarbeit Physik
Themensteller(in): Karen Alim
Mapping network theory to network function
Networks exist as our social network, the world wide web, traffic routes but also as flow networks making up the vasculature of animals, plants, fungi and slime moulds. While a lot of measures have been developed to describe networks in general it is not clear how these measures are predicting network function via network architecture. You will quantify physical networks of the slime mould and numerically generated model networks with network theoretic measures. Mapping to slime mould behaviour and model network flow and transport function will allow you to identify predictive network theoretic measures. You will learn network theory, Matlab. Prerequisites: statistical physics. Task 1 Collect network theoretic measures from the literature and Matlab packages Task 2 Apply network theoretic measures on slime mould and model data and map their property onto the network architecture Task 3 Correlate link by link network theoretic measure and flow/transport in the link under inspection to identify measures of predictive power.
geeignet als
  • Bachelorarbeit Physik
Themensteller(in): Karen Alim

Veröffentlichungen

Changing Flows Balance Nutrient Absorption and Bacterial Growth along the Gut
Agnese Codutti (author), Jonas Cremer (author), Karen Alim (author)
2022-09-23
journal article
Physical Review Letters
DOI: 10.1103/PhysRevLett.129.138101
Memory Formation in Adaptive Networks
Komal Bhattacharyya (author), David Zwicker (author), Karen Alim (author)
2022-07-06
journal article
Physical Review Letters
DOI: 10.1103/PhysRevLett.129.028101
Changing flows balance nutrient absorption and bacterial growth along the gut
Agnese Codutti (author), Jonas Cremer (author), Karen Alim (author)
2022-02-18
other
DOI: 10.1101/2022.02.16.480685
Network architecture determines vein fate during spontaneous reorganization, with a time delay
Sophie Marbach (author), Noah Ziethen (author), Leonie Bastin (author), Felix K. Bäuerle (author), Karen Alim (author)
2021-12-30
other
DOI: 10.1101/2021.12.29.474405
Nuclei are mobile processors enabling specialization in a gigantic single-celled syncytium
Tobias Gerber (author), Cristina Loureiro (author), Nico Schramma (author), Siyu Chen (author), Akanksha Jain (author), Anne Weber (author), Anne Weigert (author), Malgorzata Santel (author), Karen Alim (author), Barbara Treutlein (author), J. Gray Camp (author)
2021-04-30
other
DOI: 10.1101/2021.04.29.441915
Encoding memory in tube diameter hierarchy of living flow network
Mirna Kramar (author), Karen Alim (author)
2021-03-09
journal article
Proceedings of the National Academy of Sciences
DOI: 10.1073/pnas.2007815118
Tissue-wide integration of mechanical cues promotes effective auxin patterning
João R. D. Ramos (author), Alexis Maizel (author), Karen Alim (author)
2021-02
journal article
The European Physical Journal Plus
DOI: 10.1140/epjp/s13360-021-01204-6
Emergence of behavior in a self-organized living matter network
Philipp Fleig (author), Mirna Kramar (author), Michael Wilczek (author), Karen Alim (author)
2020-09-08
other
DOI: 10.1101/2020.09.06.285080
Living System Adapts Harmonics of Peristaltic Wave for Cost-Efficient Optimization of Pumping Performance
Felix K. Bäuerle (author), Stefan Karpitschka (author), Karen Alim (author)
2020-03-05
journal article
Physical Review Letters
DOI: 10.1103/PhysRevLett.124.098102
Robust Increase in Supply by Vessel Dilation in Globally Coupled Microvasculature
Felix J. Meigel (author), Peter Cha (author), Michael P. Brenner (author), Karen Alim (author)
2019-11-26
journal article
Physical Review Letters
DOI: 10.1103/PhysRevLett.123.228103

weitere Veröffentlichungen (insgesamt 36).

Siehe auch ORCID-Profil von Karen Alim.

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