Prof. Dr. rer. nat. Karen Alim

- Phone
- +49 89 289-12192
- Room
- PH: 3027
- k.alim@tum.de
- Links
-
Homepage
Page in TUMonline
- Group
- Theory of Biological Networks
- Job Title
- Professorship on Theory of Biological Networks
Courses and Dates
Title and Module Assignment | |||
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Art | SWS | Lecturer(s) | Dates |
Continuum Mechanics eLearning course Assigned to modules: |
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VO | 4 | Alim, K. |
Mon, 14:00–16:00, virtuell Tue, 08:30–10:00, virtuell |
Exercise to Continuum Mechanics eLearning course Assigned to modules: |
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UE | 2 |
Responsible/Coordination: Alim, K. |
dates in groups |
Current Developments in Physics of Biological Networks Assigned to modules: |
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SE | 2 | Alim, K. |
Wed, 10:00–12:00, PH 2074 |
Mentoring in the Bachelor's Program Physics Assigned to modules: |
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KO | 0.2 |
Alim, K.
Auwärter, W.
Back, C.
Bandarenka, A.
Barth, J. … (insgesamt 48)
Responsible/Coordination: Höffer von Loewenfeld, P. |
dates in groups |
Offered Bachelor’s or Master’s Theses Topics
- Biophysik der Nahrungsaufnahme im Darm
The gut microbiota has a direct impact on health, influencing how the gut digests nutrients. The microbiota itself and the nutrients are influenced by the gut contractions and the fluid flow produced by them. How do different contractions influence the dispersal of bacteria and nutrients? You will simulate the fluid flows and particle dispersal in a contracting tube (possible methodologies: COMSOL, Matlab, C, etc.). The aim is to quantify which type of contraction mixes the nutrients and the bacteria better, helping to understand the basic principle behind gut functioning.
- suitable as
- Master’s Thesis Condensed Matter Physics
- Master’s Thesis Biophysics
- Master’s Thesis Applied and Engineering Physics
- Master’s Thesis Biomedical Engineering and Medical Physics
- Master’s Thesis Matter to Life
- Master’s Thesis Theoretical and Mathematical Physics
- Supervisor: Karen Alim
- Ordnung im lebendigen Strömungsnetzwerken
Der intelligente Schleimpilz Physarum polycephalum ist dafür bekannt, dass er seinen netzförmigen Körper anpasst, um komplexe Probleme zu lösen, wie z.B. den kürzesten Weg durch ein Labyrinth zu finden oder das Problem des Handlungsreisenden zu lösen. Wie kann ein hirnloses Lebewesen solch komplexe Aufgaben bewältigen? Unsere Antwort: mit Hilfe der Physik von Strömungsnetzen. Finde heraus, wie Physarum sein Netzwerk anpasst, indem Du seine Netzwerkarchitektur quantifizierst und nach Skalierungsgesetzen suchst. Vorraussetzung: Statistische Physik. Zu verwendende und zu erlernende Werkzeuge: Matlab-Programmierung, Physik von laminaren Strömungen in Netzwerken, möglicherweise auch Zellkultur- und Hellfeldmikroskopie.
The smart slime mould Physarum polycephalum is renowned for adapting its network-shaped body to solve complex problems like finding the shortest path through a maze or solving the traveling salesman problem. How can a brainless critter accomplish such complex tasks? Our answer: by using the physics of flow networks. Find out how Physarum adapts its network by quantifying its network architecture searching for scaling laws in flow networks. Prerequisite: Statistical Physics. Tools to be used and learned: Matlab programming, physics of laminar flows in networks, potentially also cell culture and brightfieqld microscopy.
- suitable as
- Bachelor’s Thesis Physics
- Supervisor: Karen Alim
- Smoke in a white smoker
White smokers are likely the cradle of life. Their pores and tunnels allow for pockets of catalytic sites that fuel reactions at the very origin of life. How do these catalytic sites form and grow with the smoker? You will map out the structure of two-dimensional smoker models generated in William Orsi’s lab at LMU. You will then use your maps to simulate the flow and transport of reactants with the flow through the smoker. Methods: Matlab, Image Analysis, Statistical Physics, Stochastic Processes, Fluid Physics. Prerequisites: Statistical Physics and fascination for the marvels of nature.
- suitable as
- Master’s Thesis Condensed Matter Physics
- Master’s Thesis Biophysics
- Master’s Thesis Applied and Engineering Physics
- Master’s Thesis Matter to Life
- Master’s Thesis Theoretical and Mathematical Physics
- Supervisor: Karen Alim
Publications
- Emergence of behavior in a self-organized living matter network
- Philipp Fleig (author), Mirna Kramar (author), Michael Wilczek (author), Karen Alim (author)
- 2020-09-08
- other
- DOI: 10.1101/2020.09.06.285080
- Living System Adapts Harmonics of Peristaltic Wave for Cost-Efficient Optimization of Pumping Performance
- Felix K. Bäuerle (author), Stefan Karpitschka (author), Karen Alim (author)
- 2020-03-05
- journal article
- Physical Review Letters
- DOI: 10.1103/PhysRevLett.124.098102
- Robust Increase in Supply by Vessel Dilation in Globally Coupled Microvasculature
- Felix J. Meigel (author), Peter Cha (author), Michael P. Brenner (author), Karen Alim (author)
- 2019-11-26
- journal article
- Physical Review Letters
- DOI: 10.1103/PhysRevLett.123.228103
- Tissue-wide integration of mechanical cues promotes efficient auxin patterning
- João R. D. Ramos (author), Alexis Maizel (author), Karen Alim (author)
- 2019-10-28
- other
- DOI: 10.1101/820837
- The emergent Yo-yo movement of nuclei driven by collective cytoskeletal remodeling in pseudo-synchronous mitotic cycles
- 2019-06-06
- other
- []
- URL: http://dx.doi.org/10.1101/662965
- DOI: 10.1101/662965
- Order parameter allows classification of planar graphs based on balanced fixed points in the Kuramoto model
- 2019-05-23
- journal article
- Physical Review E
- URL: http://dx.doi.org/10.1103/physreve.99.052308
- DOI: 10.1103/physreve.99.052308
- ISSN: 2470-0045
- ISSN: 2470-0053
- Controlling effective dispersion within a channel with flow and active walls
- 2019-01-08
- other
- ARXIV: arXiv:1901.03697v1
- Oscillatory fluid flow drives scaling of contraction wave with system size
- Jean-Daniel Julien (author), Karen Alim (author)
- 2018-10-16
- journal article
- Proceedings of the National Academy of Sciences
- DOI: 10.1073/pnas.1805981115
- Flow rate of transport network controls uniform metabolite supply to tissue
- Felix J. Meigel (author), Karen Alim (author)
- 2018-05-31
- journal article
- Journal of The Royal Society Interface
- DOI: 10.1098/rsif.2018.0075
- Fluid flows shaping organism morphology
- Karen Alim (author)
- 2018-05-26
- journal article
- Philosophical Transactions of the Royal Society B: Biological Sciences
- DOI: 10.1098/rstb.2017.0112
further publications (total of 29).
See ORCID profile of Karen Alim as well.