Prof. Dr. rer. nat. Karen Alim
- Telefon
- +49 89 289-12192
- Raum
- 036
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k.alim@tum.de
frauenbeauftragte@ph.tum.de (Frauenbeauftragte des Physik-Departments) - Links
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Homepage
Visitenkarte in TUMonline
- Arbeitsgruppe
- Theorie biologischer Netzwerke
- Funktionen
- Mitglied des Fakultätsrats
- Frauenbeauftragte des Physik-Departments
- Professur für Theorie biologischer Netzwerke
Lehrveranstaltungen und Termine
Titel und Modulzuordnung | |||
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Art | SWS | Dozent(en) | Termine |
Fortgeschrittene statistische Physik eLearning-Kurs Zuordnung zu Modulen: |
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VO | 4 | Alim, K. |
Di, 08:00–10:00, PH 1121 Fr, 10:00–12:00, PH 1121 |
Aktuelle Entwicklungen zur Physik biologischer Netzwerke Zuordnung zu Modulen: |
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PS | 2 | Alim, K. |
Mi, 10:00–12:00, CPA EG.006B Mi, 10:00–12:00, CPA EG.006B sowie einzelne oder verschobene Termine |
Übung zu Fortgeschrittene statistische Physik Zuordnung zu Modulen: |
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UE | 2 |
Leitung/Koordination: Alim, K. |
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Journal Club Biological Physics and Morphogenesis
Zuordnung zu Modulen: |
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SE | 2 | Alim, K. |
Do, 13:00–15:00, CPA EG.006B sowie einzelne oder verschobene Termine |
Repetitorium zu Aktuelle Entwicklungen zur Physik biologischer Netzwerke Zuordnung zu Modulen: |
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RE | 2 |
Leitung/Koordination: Alim, K. |
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Tag der Physikerinnen aktuelle Informationen Zuordnung zu Modulen: |
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KO | 0.1 | Alim, K. |
einzelne oder verschobene Termine |
Tutorenseminar zu Fortgeschrittene statistische Physik Diese Lehrveranstaltung ist keinem Modul zugeordnet. |
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SE | 2 | Alim, K. |
Ausgeschriebene Angebote für Abschlussarbeiten
- Active response by adaptation of mechanical properties?
The complex behavior of the giant cell Physarum polycephalum finds its origin in the versatile transformation of liquid cytoplasm to gel-like actin-myosin meshwork making up the tube walls and vice versa. These active mechanics allow the organism to recycle its’ gel-like tubes at its rear and move it in its fluid form to the front, where it grows. Also, responding to stimuli like food, touch, or light, a change in cytoplasm viscosity seems to initiate the response. Yet, what are the mechanical properties of the liquid cytoplasm, and how much do they change upon stimulation? Do the mechanical properties of the cytoplasm change with the location in the cell? The measure of the mechanical properties of cells is challenging, but one can probe their visco-elasticity by tracking injected micron-sized beads - a technique called microrheology. You will measure the mechanical properties of cytoplasm extracts and grown Physarum, and quantify how they change upon stimulation by passive and active microrheology. Task 1: Establish cytoplasm extraction following previous work in the literature. Task 2: Perform passive microrheology on cytoplasmic droplets without and with stimulation (light, food, drugs) and analyze your data quantitatively. Task 3: Establish active microrheology to extract cytoplasm viscosity in different parts of Physarum’s network.
- geeignet als
- Bachelorarbeit Physik
- Themensteller(in): Karen Alim
- Mapping network theory to network function
- Networks exist as our social network, the world wide web, traffic routes but also as flow networks making up the vasculature of animals, plants, fungi and slime moulds. While a lot of measures have been developed to describe networks in general it is not clear how these measures are predicting network function via network architecture. You will quantify physical networks of the slime mould and numerically generated model networks with network theoretic measures. Mapping to slime mould behaviour and model network flow and transport function will allow you to identify predictive network theoretic measures. You will learn network theory, Matlab. Prerequisites: statistical physics. Task 1 Collect network theoretic measures from the literature and Matlab packages Task 2 Apply network theoretic measures on slime mould and model data and map their property onto the network architecture Task 3 Correlate link by link network theoretic measure and flow/transport in the link under inspection to identify measures of predictive power.
- geeignet als
- Bachelorarbeit Physik
- Themensteller(in): Karen Alim
Veröffentlichungen
- Changing Flows Balance Nutrient Absorption and Bacterial Growth along the Gut
- Agnese Codutti (author), Jonas Cremer (author), Karen Alim (author)
- 2022-09-23
- journal article
- Physical Review Letters
- DOI: 10.1103/PhysRevLett.129.138101
- Memory Formation in Adaptive Networks
- Komal Bhattacharyya (author), David Zwicker (author), Karen Alim (author)
- 2022-07-06
- journal article
- Physical Review Letters
- DOI: 10.1103/PhysRevLett.129.028101
- Changing flows balance nutrient absorption and bacterial growth along the gut
- Agnese Codutti (author), Jonas Cremer (author), Karen Alim (author)
- 2022-02-18
- other
- DOI: 10.1101/2022.02.16.480685
- Network architecture determines vein fate during spontaneous reorganization, with a time delay
- Sophie Marbach (author), Noah Ziethen (author), Leonie Bastin (author), Felix K. Bäuerle (author), Karen Alim (author)
- 2021-12-30
- other
- DOI: 10.1101/2021.12.29.474405
- Nuclei are mobile processors enabling specialization in a gigantic single-celled syncytium
- Tobias Gerber (author), Cristina Loureiro (author), Nico Schramma (author), Siyu Chen (author), Akanksha Jain (author), Anne Weber (author), Anne Weigert (author), Malgorzata Santel (author), Karen Alim (author), Barbara Treutlein (author), J. Gray Camp (author)
- 2021-04-30
- other
- DOI: 10.1101/2021.04.29.441915
- Encoding memory in tube diameter hierarchy of living flow network
- Mirna Kramar (author), Karen Alim (author)
- 2021-03-09
- journal article
- Proceedings of the National Academy of Sciences
- DOI: 10.1073/pnas.2007815118
- Tissue-wide integration of mechanical cues promotes effective auxin patterning
- João R. D. Ramos (author), Alexis Maizel (author), Karen Alim (author)
- 2021-02
- journal article
- The European Physical Journal Plus
- DOI: 10.1140/epjp/s13360-021-01204-6
- Emergence of behavior in a self-organized living matter network
- Philipp Fleig (author), Mirna Kramar (author), Michael Wilczek (author), Karen Alim (author)
- 2020-09-08
- other
- DOI: 10.1101/2020.09.06.285080
- Living System Adapts Harmonics of Peristaltic Wave for Cost-Efficient Optimization of Pumping Performance
- Felix K. Bäuerle (author), Stefan Karpitschka (author), Karen Alim (author)
- 2020-03-05
- journal article
- Physical Review Letters
- DOI: 10.1103/PhysRevLett.124.098102
- Robust Increase in Supply by Vessel Dilation in Globally Coupled Microvasculature
- Felix J. Meigel (author), Peter Cha (author), Michael P. Brenner (author), Karen Alim (author)
- 2019-11-26
- journal article
- Physical Review Letters
- DOI: 10.1103/PhysRevLett.123.228103
weitere Veröffentlichungen (insgesamt 36).
Siehe auch ORCID-Profil von Karen Alim.