Franz Pfeiffer appointed as Carl von Linde Senior Fellows at IAS
2015-01-23 – News from Physics Department
Conventional X-ray CT techniques produce images or 3D representations based on the difference in X-ray transmission of different bodily structures. The novel technique of dark-field imaging – developed in Pfeiffer’s research group – greatly enhances the contrast and sensitivity of X-ray images.
Due to the fact that both the wavelength and the interaction with matter are inherently different for visible light and X-rays, the experimental implementation is much more challenging for X-rays than in optical microscopy. Pfeiffer’s solution to the problem is an imaging interferometer using three diffraction gratings – a profound technological hurdle, considering the short wavelengths of X-rays compared to visible light and the large image areas required for medical imaging.
Development of first clinical dark-field CT prototype
Having established these novel techniques as a means of studying mice in-vivo with unprecedented detail, Franz Pfeiffer will use the fellowship program to solve the remaining technical and conceptual scientific challenges for a first implementation into a clinical dark-field CT prototype for human diagnostics. It is hoped that, once the technique can then finally be translated to the clinics, an early detection and screening of chronic obstructive pulmonary disease (COPD) will become possible and allow early therapeutic interventions for a range of lung diseases.
The research will be carried out in interdisciplinary collaborations between physics and medicine, involving collaborations with the Klinikum Großhadern, the Klinikum rechts der Isar, and the Helmholtz Zentrum München under the framework of the Excellence Cluster Munich-Centre for Advanced Photonics (MAP).
Carl von Linde Senior Fellowships at TUM
The IAS awards up to two Carl von Linde Senior Fellowships per year to outstanding TUM faculty members who “intend to develop innovative, high-risk topics in their scientific research areas, if possible within a trans-disciplinary team”.
TUM-IAS Fellowships last three years and offer the opportunity to fully devote time to the development of the new research area, completely unrestricted by teaching obligations or non relevant administrative functions. It is up to the awardee to plan the duration of the Fellowship according to his requirements.
- Dr. Johannes Wiedersich
- Prof. Dr. Franz Pfeiffer