Mammalian Cell Engineering (CH0170)
Course 0000001729 in SS 2024
General Data
| Course Type | lecture with integrated exercises |
|---|---|
| Semester Weekly Hours | 3 SWS |
| Organisational Unit | Associate Professorship of Neurobiological Engineering (Prof. Westmeyer) |
| Lecturers |
Gil Westmeyer |
| Dates |
Fri, 10:00–13:00, MIBE E.126 and 2 singular or moved dates |
Further Information
Courses are together with exams the building blocks for modules. Please keep in mind that information on the contents, learning outcomes and, especially examination conditions are given on the module level only – see section "Assignment to Modules" above.
| additional remarks | In this interactive seminar, we engage in an in-depth exploration of the foundational concepts and principles of synthetic biology as they pertain to mammalian cell manipulation for biomedical applications. Through interactive discourse, we investigate central cellular processes, highlighting their relevance within the field of biomedicine. Topics covered encompass CRISPR-based gene editing, DNA and RNA gene expression modification techniques, cutting-edge molecular cloning strategies, de novo protein engineering principles, the incorporation of non-canonical amino acids, advanced reporter gene engineering, and the utilization of genetically controlled actuators to manipulate cellular processes at the tissue level. To facilitate comprehension, a systematic review of selected literature is conducted, enabling students to assess the biological engineering of mammalian cells for regenerative medicine and tissue engineering approaches. Acknowledging the profound impact of synthetic biology on biomedicine and society, ethical considerations pertaining to gene editing, cellular therapies, and other applications are comprehensively discussed. Culminating the course, students are tasked with presenting an elevator pitch for an innovative synthetic biology concept that addresses a specific need or overcomes a biotechnological challenge. Students are expected to articulate precise design specifications and outline how these can be achieved through systematic experimentation. During class presentations, students engage in detailed discussions regarding technical aspects and are anticipated to address potential risks or obstacles that may arise while implementing their concepts. |
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| Links |
E-Learning course (e. g. Moodle) TUMonline entry |
Equivalent Courses (e. g. in other semesters)
| Semester | Title | Lecturers | Dates |
|---|---|---|---|
| WS 2023/4 | Mammalian Cell Engineering (CH0170) | Westmeyer, G. | |
| SS 2023 | Mammalian Cell Engineering (CH0170) | Westmeyer, G. |
Wed, 09:00–12:00, MIBE E.126 |
| WS 2022/3 | Mammalian Cell Engineering (CH0170) | Westmeyer, G. |
Wed, 09:00–12:00 |
| SS 2022 | Mammalian Cell Engineering (CH0170) | Westmeyer, G. |
Wed, 09:00–13:00, MIBE E.126 and singular or moved dates |
| WS 2021/2 | Mammalian Cell Engineering | Westmeyer, G. |