Mammalian Cell Engineering (CH0170)
Course 0000001729 in WS 2023/4
General Data
| Course Type | lecture with integrated exercises |
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| Semester Weekly Hours | 3 SWS |
| Organisational Unit | Associate Professorship of Neurobiological Engineering (Prof. Westmeyer) |
| Lecturers |
Gil Westmeyer |
| Dates |
Further Information
Courses are together with exams the building blocks for modules. Please keep in mind that information on the contents, learning outcomes and, especially examination conditions are given on the module level only – see section "Assignment to Modules" above.
| additional remarks | In this interactive seminar, we delve into fundamental concepts and principles of synthetic biology as they relate to working with mammalian cells for biomedical applications. Through interactive discussions, we explore key concepts of central cellular processes, emphasizing their application in the field of biomedicine. Topics covered include CRISPR-based gene editing, DNA and RNA gene expression modifications, state-of-the-art molecular techniques, de novo protein engineering principles, incorporation of non-canonical amino acids, advanced reporter gene engineering, and the use of genetically controlled actuators to manipulate cellular processes at the tissue level.To enhance understanding, selected literature is reviewed systematically, enabling students to evaluate the biological engineering of mammalian cells for regenerative medicine and tissue engineering approaches. Given the profound impact of synthetic biology on biomedicine and society, ethical considerations related to gene editing, cellular therapies, and other applications are also discussed.At the end of the class, students are tasked with delivering an elevator pitch for an innovative biological engineering concept that addresses a specific need or overcomes a biotechnological challenge. Students should define the new concept's precise design specifications and outline how these can be achieved through systematic experimental work. During class presentations, students face detailed questioning regarding technical aspects and are expected to address potential risks or obstacles that may arise while implementing their concepts. |
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| Links |
E-Learning course (e. g. Moodle) TUMonline entry |
Equivalent Courses (e. g. in other semesters)
| Semester | Title | Lecturers | Dates |
|---|---|---|---|
| SS 2024 | Mammalian Cell Engineering (CH0170) | Westmeyer, G. |
Fri, 10:00–13:00, MIBE E.126 and singular or moved dates |
| SS 2023 | Mammalian Cell Engineering (CH0170) | Westmeyer, G. |
Wed, 09:00–12:00, MIBE E.126 |
| WS 2022/3 | Mammalian Cell Engineering (CH0170) | Westmeyer, G. |
Wed, 09:00–12:00 |
| SS 2022 | Mammalian Cell Engineering (CH0170) | Westmeyer, G. |
Wed, 09:00–13:00, MIBE E.126 and singular or moved dates |
| WS 2021/2 | Mammalian Cell Engineering | Westmeyer, G. |