Parameter Estimation for Dynamic Biological Systems
Course 0000001128 in SS 2014
General Data
| Course Type | lecture |
|---|---|
| Semester Weekly Hours | 2 SWS |
| Organisational Unit | Research Department Mathematics Centre |
| Lecturers |
Jan Hasenauer Fabian Theis |
| Dates |
Assignment to Modules
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MA5612: Statistical Inference for Dynamical Systems / Statistical Inference for Dynamical Systems
This module is included in the following catalogs:- Specialization Modules in Elite-Master Program Theoretical and Mathematical Physics (TMP)
Further Information
Courses are together with exams the building blocks for modules. Please keep in mind that information on the contents, learning outcomes and, especially examination conditions are given on the module level only – see section "Assignment to Modules" above.
| additional remarks | Mathematical models are nowadays essential for the quantitative assessment of technical, physical, chemical, and biological processes. While a broad class of models is used in the different field, almost all models share one common property: the need for accurate parameter values. Due to experimental constraints, many parameters cannot be measured directly, but have to be estimated from the available experimental data. In this course, we will introduce deterministic modeling approaches for biochemical reaction networks. These modeling approaches can be used to describe, e.g., signal transduction and metabolic processes. For these models the respective parameter estimation problem will be formulated and methods will be presented to solve these problems. As parameter estimates carry uncertainties due to limited amounts of data and measurement noise, we furthermore provide methods for a rigorous analysis of parameter uncertainties. This is crucial to evaluate the model uncertainties as well as the predictive power of models. The participants will gather hands-on experiences with parameter estimation and uncertainty analysis, including the implementation of own models and estimation procedures in MATLAB. The estimation methods are presented in the context of biological processes, but the approaches are applicable in many other fields. |
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| Links |
E-Learning course (e. g. Moodle) TUMonline entry |
Equivalent Courses (e. g. in other semesters)
| Semester | Title | Lecturers | Dates |
|---|---|---|---|
| SS 2019 | Statistical Inference for Dynamical Systems [MA5612] | Schubert, B. |
Wed, 10:15–11:45, MI 02.08.011 |
| SS 2018 | Statistical Inference for Dynamical Systems [MA5612] | Hasenauer, J. |
Wed, 10:15–11:45, MI 02.08.011 |
| SS 2017 | Statistical Inference for Dynamical Systems [MA5612] | Hasenauer, J. |
Wed, 10:15–11:45, MI 02.08.011 |
| SS 2016 | Statistical Inference for Dynamical Systems | Hasenauer, J. Theis, F. |
Wed, 10:15–11:45, MI 02.08.011 |
| SS 2015 | Parameter Estimation for Dynamic Biological Systems | Hasenauer, J. Theis, F. |
Wed, 10:15–11:45, MI 02.08.020 |