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Flow Lithography

Course 0000003094 in WS 2022/3

General Data

Course Type lecture with integrated exercises
Semester Weekly Hours 4 SWS
Organisational Unit Assistant Professorship of Control and Manipulation of Microscale Living Objects (Prof. Destgeer)
Lecturers Ghulam Destgeer
Mehmet Akif Sahin
Helen Werner
Dates Fri, 09:00–12:00

Assignment to Modules

Further Information

Courses are together with exams the building blocks for modules. Please keep in mind that information on the contents, learning outcomes and, especially examination conditions are given on the module level only – see section "Assignment to Modules" above.

additional remarks Structured microparticles, with unique shapes, customizable sizes, multiple materials, and spatially-defined chemistries, are leading the way for emerging ‘lab on a particle’ technologies. These microparticles with engineered designs find applications in multiplexed diagnostics, drug delivery, single-cell secretion assays, single-molecule detection assays, high throughput cytometry, micro-robotics, self-assembly, and tissue engineering. In this course, we will learn about the state-of-the-art particle manufacturing technologies based on flow-assisted photolithography performed inside microfluidic channels. Important physiochemical concepts will be discussed to provide a basis for understanding the fabrication technologies. These photolithography technologies will be compared based on the structural as well as compositional complexity of the fabricated particles. Particles will be categorized, from 1D to 3D particles, based on the number of dimensions that can be independently controlled during the fabrication process. After discussing the pros and cons of the individual techniques, important applications of the fabricated particles will be covered. Course topics: 1 Introduction to flow assisted lithography 2 Important physio-chemical concepts 2.1 Polymerization inside microfluidic channels 2.2 Single-phase flows in microfluidic channel 2.3 Microchannel material 2.4 Multi-phase flow in microfluidic channel 2.5 Particle-templated droplet formation 3 Categorization based on particle dimensions 3.1 1D, 1.5D, 2D, 2.5D, and 3D particles 4 Flow-assisted particle fabrication techniques 4.1 1D particles: droplet microfluidics lithography… 4.2 1.5D particles: non-spherical lithography… 4.3 2D particles: continuous flow lithography… 4.4 2.5D particles: hydrodynamic flow lithography… 4.5 3D particles: inertial flow lithography… 5 Applications of particles 5.1 Particle-templated droplet formation 5.2 Cell-laden hydrogels (tissue scaffolds) 5.3 Diagnostics assays 5.4 Cell culture on the particles (cell-carrier)
Links TUMonline entry

Equivalent Courses (e. g. in other semesters)

SS 2024 Flow Lithography Destgeer, G. Sahin, M. Werner, H. Mon, 09:00–12:00
and singular or moved dates
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