Courses are together with exams the building blocks for modules. Please keep in mind that information on the contents, learning outcomes and, especially examination conditions are given on the module level only – see section "Assignment to Modules" above.
||The block course will start by introducing the field of biosensors including the medical and economic drivers for important applications. We will cover basic operation principles of the different biosensor classes, give the theoretical background for electrochemical and optical transduction mechanisms and introduce the types of biorecognition elements used in current sensor concepts. We will then proceed to discuss in detail major biosensor classes and architectures including application examples ranging from molecular to cell-based sensors. We will highlight disposable sensors and fabrication methods for point-of-care applications and finally address recent developments in new sensor concepts based on single-molecule techniques and stochastic sensing.
Course topics (example):
• Introduction to biosensors: historical developments, applications and predicted trends
• Introduction to biological recognition elements for sensor concepts
• Physical transduction mechanisms
• Enzymatic sensor concepts and selected examples (glucose oxidase enzyme electrode)
• Cell-based biosensors
• In-vivo biosensors
• Disposable biosensors in point-of-care applications: Concepts and fabrication
• Advanced biosensor methods (stochastic detection, single-molecule techniques)