Physical chemistry basics of DNA and genetic information

Module PH2154

This module handbook serves to describe contents, learning outcome, methods and examination type as well as linking to current dates for courses and module examination in the respective sections.

Basic Information

PH2154 is a semester module in German or English language at Master’s level which is offered in summer semester.

This Module is included in the following catalogues within the study programs in physics.

  • General catalogue of special courses
  • Specific catalogue of special courses for Biophysics

If not stated otherwise for export to a non-physics program the student workload is given in the following table.

Total workloadContact hoursCredits (ECTS)
150 h 75 h 5 CP

Responsible coordinator of the module PH2154 is Günther Woehlke.

Content, Learning Outcome and Preconditions

Content

Information encoding in DNA; DNA topology and biological adaptations of topology; advanced topics of DNA replication and repair; gene expression and it regulation; genetic switches; systems biology of genomes

Learning Outcome

After successful attendance, the participants are able to judge the relevance of physical-chemical basics for storage, propagation and maintenance of genetic information. The module introduces current literature and current problems of the field.

Preconditions

Biophysics in cells; advanced knowledge of molecular biology and/or genetics.

Courses, Learning and Teaching Methods and Literature

Courses and Schedule

Learning and Teaching Methods

Lecture, exercises and current literature.

Media

Lecture/script; possibly presentations

Literature

Phillips et al. (2013) Physical Biolog of the Cell. 2nd ed.

Module Exam

Description of exams and course work

In an oral exam the learning outcome is tested using comprehension questions and sample problems.

In accordance with §12 (8) APSO the exam can be done as a written test. In this case the time duration is 60 minutes.

Exam Repetition

There is a possibility to take the exam at the end of the semester.

Condensed Matter

When atoms interact things can get interesting. Fundamental research on the underlying properties of materials and nanostructures and exploration of the potential they provide for applications.

Nuclei, Particles, Astrophysics

A journey of discovery to understanding our world at the subatomic scale, from the nuclei inside atoms down to the most elementary building blocks of matter. Are you ready for the adventure?

Biophysics

Biological systems, from proteins to living cells and organisms, obey physical principles. Our research groups in biophysics shape one of Germany's largest scientific clusters in this area.