Biosensors and Bioelectronics 2
Module PH2096
Basic Information
PH2096 is a semester module in English language at Master’s level which is offered in winter semester.
This module description is valid to SS 2013.
If not stated otherwise for export to a non-physics program the student workload is given in the following table.
| Total workload | Contact hours | Credits (ECTS) |
|---|---|---|
| 150 h | 40 h | 5 CP |
Responsible coordinator of the module PH2096 is Jose Antonio Garrido Ariza.
Content, Learning Outcome and Preconditions
Content
This lecture provides general knowledge in the field of biosensors and bioelectronics. The lecture is intended to be divided into two parts, corresponding to two semesters.
The first semester will provide an introduction to physical-chemistry of the solid/water interface, an overview of electrochemistry concepts, and the operation principles of biosensors, including electrochemical sensors, optical sensors, acoustic sensors, as well as semiconductor-based sensors.
During the second semester the lecture will cover topics closer to the field of cell and molecular bioelectronics, such as membrane phenomena, generation of action potentials in living cells, cell-semiconductor interfaces, as well as electron transfer reactions in biological compounds, and transmission of information in living organisms.
Learning Outcome
After participation in this module (Biosensors and Bioelectronics 2) the student is able to:
1. Describe the physics governing voltage-gated ion channels in cell membranes, including the mathematical description of the voltage-dependent conductivity.
2. Understand and explain cell membrane phenomena such as transmembrane potential, and generation of action potentials.
3. Explain and describe the cell/transistor interface.
4. Calculate the different forms of the recorded signals with the field effect transistors. Similarly, describe the extracellular stimulation of nerve cells with FETs.
5. Understand and describe electron transfer reactions in biological systems: Marcus model for electron transfer, role of reorganization energy, etc.
Preconditions
Courses, Learning and Teaching Methods and Literature
Courses and Schedule
| Type | SWS | Title | Lecturer(s) | Dates | Links |
|---|---|---|---|---|---|
| VO | 2 | Biosensors and Bioelectronics 2 | Garrido Ariza, J. |
singular or moved dates |
documents |
Learning and Teaching Methods
lecture, projector presentation, board work
Media
lecture script, accompanying internet site, complementary literature
Literature
"Electrochemical methods: Fundamentals and Applications", A.J. Bard; Wiley
•"Physics and Chemistry of Interfaces", H.-J. Butt, Wiley
•"Bioelectrochemistry. Encyclopedia of Electrochemistry. Vol 9", G.S. Wilson, Wiley
•"Biological Membranes" O.Sten-Knudsen, Cambridge
Module Exam
Description of exams and course work
In an oral exam the learning outcome is tested using comprehension questions and sample problems.
In accordance with §12 (8) APSO the exam can be done as a written test. In this case the time duration is 60 minutes.
Exam Repetition
The exam may be repeated at the end of the semester.