Biosensoren und Bioelektronik 1
Biosensors and Bioelectronics 1

This lecture provides general knowledge in the field of biosensors and bioelectronics. The lecture is intended to be divided into two parts, corresponding to two semesters.

The first semester will provide an introduction to physical-chemistry of the solid/water interface, an overview of electrochemistry concepts, and the operation principles of biosensors, including electrochemical sensors, optical sensors, acoustic sensors, as well as semiconductor-based sensors.

During the second semester the lecture will cover topics closer to the field of cell and molecular bioelectronics, such as membrane phenomena, generation of action potentials in living cells, cell-semiconductor interfaces, as well as electron transfer reactions in biological compounds, and transmission of information in living organisms.

After participation in this module (Biosensors and Bioelectronics 1) the student is able to:
1. Understand and explain the basics of electrode potentials, and double layer formation at metal/electrolyte and semiconductor/electrolyte interfaces
2. Describe basic aspects of electron transfer processes at metal and semiconductor electrodes, with particular attention to mass-limited electron transfer and kinetic limited electron transfer processes.
3. Understand and describe the operation principles of electrochemical biosensors, such as amperometric and potentiometric sensors
4. Understand and describe the operation principles of biosensors based on semiconductor field-effect devices.
5. Understand and describe the operation principles of optical biosensors (fiber biosensors, surface plasmon resonance -SPR- biosensors, etc).
6. Understand and describe the operation principles of piezo and acoustic biosensors (quartz crystal microbalance, surface acoustic wave -SAW- biosensors).

Keine Vorkenntnisse nötig, die über die Zulassungsvoraussetzungen zum Masterstudium hinausgehen.

lecture, projector presentation, board work

lecture script, accompanying internet site, complementary literature

• "Electrochemical methods: Fundamentals and Applications", A.J. Bard; Wiley
• "Physics and Chemistry of Interfaces", H.-J. Butt, Wiley
• "Bioelectrochemistry. Encyclopedia of Electrochemistry. Vol 9", G.S. Wilson, Wiley
• "Biological Membranes" O.Sten-Knudsen, Cambridge

In einer mündlichen Prüfung wird das Erreichen der Lernergebnisse durch Verständnisfragen und Beispielaufgaben bewertet.

Die Prüfung kann in Übereinstimmung mit §12 (8) APSO auch schriftlich abgehalten werden, in diesem Fall ist der Richtwert für die Prüfungsdauer 60 Minuten.