Kinetics of Cellular Reactions

Module PH2023

This module handbook serves to describe contents, learning outcome, methods and examination type as well as linking to current dates for courses and module examination in the respective sections.

Basic Information

PH2023 is a semester module in German or English language at Master’s level which is offered in winter semester.

This Module is included in the following catalogues within the study programs in physics.

  • General catalogue of special courses
  • Specific catalogue of special courses for Biophysics

If not stated otherwise for export to a non-physics program the student workload is given in the following table.

Total workloadContact hoursCredits (ECTS)
150 h 60 h 5 CP

Responsible coordinator of the module PH2023 is Günther Woehlke.

Content, Learning Outcome and Preconditions

Content

Fundamentals of Steady State (Michaelis-Menten, Briggs-Haldane,...); Detection of Reaction Intermediates; Mathematical Descriptions of Kinetic Models; Allosteric Models; Single-molecule Kinetics; Examples: Kinesin, Processivity and Randomness; Proofreading Mechanisms

Learning Outcome

Understanding and application of all fundamental kinetic models; transfer of kinetic schemes to quantitative models (using Mathematica or other computer languages); ability to discern global kinetic models and kinetic steps; understanding of differences between ensemble measurements and single-molecule assays.

Preconditions

Basic understanding of physical chemistry

Courses, Learning and Teaching Methods and Literature

Courses and Schedule

Learning and Teaching Methods

As requested

Media

lecture, seminar, others

Literature

Given upon request.

Module Exam

Description of exams and course work

In an oral exam the learning outcome is tested using comprehension questions and sample problems.

In accordance with §12 (8) APSO the exam can be done as a written test. In this case the time duration is 60 minutes.

Exam Repetition

There is a possibility to take the exam at the end of the semester. There is a possibility to take the exam in the following semester.

Condensed Matter

When atoms interact things can get interesting. Fundamental research on the underlying properties of materials and nanostructures and exploration of the potential they provide for applications.

Nuclei, Particles, Astrophysics

A journey of discovery to understanding our world at the subatomic scale, from the nuclei inside atoms down to the most elementary building blocks of matter. Are you ready for the adventure?

Biophysics

Biological systems, from proteins to living cells and organisms, obey physical principles. Our research groups in biophysics shape one of Germany's largest scientific clusters in this area.