Theoretical Biophysics 2

Module PH2018

This module handbook serves to describe contents, learning outcome, methods and examination type as well as linking to current dates for courses and module examination in the respective sections.

Basic Information

PH2018 is a semester module in English language at Master’s level which is offered in summer semester.

This Module is included in the following catalogues within the study programs in physics.

  • General catalogue of special courses
  • Specific catalogue of special courses for Biophysics

If not stated otherwise for export to a non-physics program the student workload is given in the following table.

Total workloadContact hoursCredits (ECTS)
150 h 40 h 5 CP

Responsible coordinator of the module PH2018 is Martin Zacharias.

Content, Learning Outcome and Preconditions


  • Thermodynamics and kinetics of association
  • Statistical mechanics of binding reactions
  • Driving forces for association Protein-DNA and Protein-RNA interaction
  • Prediction of binding
  • Multiple interactions
  • Allosteric interactions
  • Diffusion and transport processes
  • Biological membranes
  • Active and passive transport
  • Interaction networks, topology and dynamics
  • Metabolic and regulatory networks
  • Signal transduction

Learning Outcome

After participation in the Module the student is able to understand and apply the statistical and thermodynamic concepts of binding and association processes of biomolecules. The student will have an understanding of theoretical models to describe allosteric effects and transport processes coupled to binding events. Furthermore the student obtains an overview on the theoretical concepts to describe the network character of metabolic and regulatory processes in biophysics.


Theoretische Biophysik I

Courses, Learning and Teaching Methods and Literature

Courses and Schedule

VO 2 Theoretische Biophysik II einzelne oder verschobene Termine

Learning and Teaching Methods

lecture, exercises in individual and group work, discussion


practise sheets


  • Jacob Israelachvelli, Intermolecular and surface forces, Academic Press
  • Aurel Popescu, Valerica Raicu, Integrated Molecular and Cellular Biophysics, Springer Press

Module Exam

Description of exams and course work

In an oral exam the learning outcome is tested using comprehension questions and sample problems.

In accordance with §12 (8) APSO the exam can be done as a written test. In this case the time duration is 60 minutes.

Exam Repetition

There is a possibility to take the exam at the end of the semester. There is a possibility to take the exam in the following semester.

Condensed Matter

When atoms interact things can get interesting. Fundamental research on the underlying properties of materials and nanostructures and exploration of the potential they provide for applications.

Nuclei, Particles, Astrophysics

A journey of discovery to understanding our world at the subatomic scale, from the nuclei inside atoms down to the most elementary building blocks of matter. Are you ready for the adventure?


Biological systems, from proteins to living cells and organisms, obey physical principles. Our research groups in biophysics shape one of Germany's largest scientific clusters in this area.