Theoretical Biophysics 2

Module PH2018

This module handbook serves to describe contents, learning outcome, methods and examination type as well as linking to current dates for courses and module examination in the respective sections.

Basic Information

PH2018 is a semester module in English language at Master’s level which is offered in summer semester.

This module description is valid to SS 2013.

If not stated otherwise for export to a non-physics program the student workload is given in the following table.

Total workload	Contact hours	Credits (ECTS)
150 h	40 h	5 CP

Responsible coordinator of the module PH2018 is Martin Zacharias.

Content, Learning Outcome and Preconditions

Content

Thermodynamics and kinetics of association
Statistical mechanics of binding reactions
Driving forces for association Protein-DNA and Protein-RNA interaction
Prediction of binding
Multiple interactions
Allosteric interactions
Diffusion and transport processes
Biological membranes
Active and passive transport
Interaction networks, topology and dynamics
Metabolic and regulatory networks
Signal transduction

Learning Outcome

After participation in the Module the student is able to understand and apply the statistical and thermodynamic concepts of binding and association processes of biomolecules. The student will have an understanding of theoretical models to describe allosteric effects and transport processes coupled to binding events. Furthermore the student obtains an overview on the theoretical concepts to describe the network character of metabolic and regulatory processes in biophysics.

Preconditions

Theoretische Biophysik I

Courses, Learning and Teaching Methods and Literature

Learning and Teaching Methods

lecture, exercises in individual and group work, discussion

Media

practise sheets

Literature

Jacob Israelachvelli, Intermolecular and surface forces, Academic Press
Aurel Popescu, Valerica Raicu, Integrated Molecular and Cellular Biophysics, Springer Press

Module Exam

Description of exams and course work

In an oral exam the learning outcome is tested using comprehension questions and sample problems.

In accordance with §12 (8) APSO the exam can be done as a written test. In this case the time duration is 60 minutes.

Exam Repetition

The exam may be repeated at the end of the semester. There is a possibility to take the exam in the following semester.