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Physical Biology of the Cell 1

Module PH2013

This module handbook serves to describe contents, learning outcome, methods and examination type as well as linking to current dates for courses and module examination in the respective sections.

Module version of WS 2016/7

There are historic module descriptions of this module. A module description is valid until replaced by a newer one.

Whether the module’s courses are offered during a specific semester is listed in the section Courses, Learning and Teaching Methods and Literature below.

available module versions
WS 2022/3WS 2021/2WS 2020/1WS 2019/20WS 2018/9WS 2017/8WS 2016/7WS 2015/6WS 2010/1

Basic Information

PH2013 is a semester module in German language at Master’s level which is offered in winter semester.

This Module is included in the following catalogues within the study programs in physics.

  • Specific catalogue of special courses for Biophysics
  • Specific catalogue of special courses for Applied and Engineering Physics
  • Focus Area Bio-Sensors in M.Sc. Biomedical Engineering and Medical Physics
  • Elective Modules Natural Sciences in the Master Program Matter to Life
  • Complementary catalogue of special courses for condensed matter physics
  • Complementary catalogue of special courses for nuclear, particle, and astrophysics

If not stated otherwise for export to a non-physics program the student workload is given in the following table.

Total workloadContact hoursCredits (ECTS)
150 h 75 h 5 CP

Responsible coordinator of the module PH2013 in the version of WS 2016/7 was Andreas Bausch.

Content, Learning Outcome and Preconditions


  • Einführung: Was sind biologische Makromoleküle?
  • Makromolekulare Längen-, Zeit-, Kraft-, und Energieskalen
  • Makromolekulare Fluidmechanik
  • Makromolekular-Diffusion
  • Makromolekulare Assoziation und Dissoziation (frei/in Potentialen)
  • Dynamik/Gleichgewicht von Zwei-Zustandssystemen
  • Dynamik/Gleichgewicht bimolekularer Reaktionen
  • Enzymkinetik
  • Dynamik molekularer Motoren
  • Biopolymer-Mechanik
  • Makromoleküle unter Kraftwirkung
  • Makromolekulare Regelkreise (Gen-Regulation, Signalverarbeitung)

Learning Outcome

Nach erfolgreicher Teilnahme an diesem Modul ist der/die Student(in) in der Lage:

  1. Biologische Makromolekülklassen und die für sie relevante physikalische Umgebung (Zeit-, Längen-, Kraftskalen etc) zu beschreiben.
  2. Wesentliche dynamische und stationäre Eigenschaften von makromolekularen Zustandsänderungen sowie von bimolekularen Reaktionen, auch in Abhängigkeit von zusätzlichen Einflüssen wie z.B wirkenden Kräften zu erklären.
  3. Begriffe wie Entropieelastizität, Dissoziationskonstante, Übergangszustand, Übergangsrate zu verstehen.
  4. Modelle zur physikalischen Beschreibung makromolekularer Regelkreise (Gen-Repression/regulierte Rekrutierung, Adaption) anzugeben und zu erklären.


Keine Vorkenntnisse nötig, die über die Zulassungsvoraussetzungen zum Masterstudium hinausgehen.

Courses, Learning and Teaching Methods and Literature

Courses and Schedule

Learning and Teaching Methods

Vortrag, Beamerpräsentation, Tafelarbeit, Übungen in Einzel- und Gruppenarbeit




  • J. Howard: "Mechanics of Motor Proteins and the Cytoskeleton"
  • P. Nelson: "Biological Physics: Energy, Information, Life"
  • R. Philipps: "Physical Biology"
  • U. Alon: "Introduction to Systems Biology"
  • M. Ptashne: "Genes and Signals"
  • L. Stryer: "Biochemistry"
  • B. Alberts: "The Cell"
  • E. Wilson: "The future of life"

Module Exam

Description of exams and course work

In a written exam the learning outcome is tested using comprehension questions and sample problems.

In accordance with §12 (8) APSO the exam can be done as an oral exam. In this case the time duration is 25 minutes.

Remarks on associated module exams

The exam for this module can be taken together with the exam to the associated follow-up module PH2014: Physical Biology of the Cell 2 / Biophysik der Zelle 2 after the follwoing semester. In this case you need to register for both exams in the following semester.

Exam Repetition

The exam may be repeated at the end of the semester. There is a possibility to take the exam in the following semester.

Current exam dates

Currently TUMonline lists the following exam dates. In addition to the general information above please refer to the current information given during the course.

Exam to Physical Biology of the Cell 1
Fri, 2024-03-01, 11:00 till 12:30 1450
till 2024-01-15 (cancelation of registration till 2024-02-23)
Mon, 2024-03-25, 11:00 till 12:30 1450
till 2024-03-21
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