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Module PH0020 [Bio Expert]

This module handbook serves to describe contents, learning outcome, methods and examination type as well as linking to current dates for courses and module examination in the respective sections.

Module version of SS 2017

There are historic module descriptions of this module. A module description is valid until replaced by a newer one.

Whether the module’s courses are offered during a specific semester is listed in the section Courses, Learning and Teaching Methods and Literature below.

available module versions
SS 2023SS 2022SS 2021SS 2020SS 2019SS 2018SS 2017SS 2011

Basic Information

PH0020 is a semester module in German language at Bachelor’s level which is offered in summer semester.

This Module is included in the following catalogues within the study programs in physics.

  • Mandatory Modules in Bachelor Programme Physics (6th Semester, Specialization BIO)

If not stated otherwise for export to a non-physics program the student workload is given in the following table.

Total workloadContact hoursCredits (ECTS)
300 h 90 h 10 CP

Responsible coordinator of the module PH0020 in the version of SS 2017 was Andreas Bausch.

Content, Learning Outcome and Preconditions


This module gives an overview of the theoretical and experimental concepts of Biophysics. 

The following topics will be introduced:

Bricks of life

  • Sugar
  • DNA
  • Proteins
  • experimental methods for structure determination


  • Michaelis Menten
  • Allosterische Kontrolle

Pattern Formation Processes in Nature

  • Reaction  Diffusions Processes
  • Embryogenesis


  • Selfassembly of Membranes
  • Nernst-Potential, Goldman Katz, Huxly-Hodgkin-Equation


  • Photosynthetic Processes
  • Fluoreszenz- und Energietransferprocesses

Aspekte der Nichtgleichgewichts-Thermodynamik

  • Onsager-Relation
  • Entropieproduction

Molecular Forces

  • Poisson-Boltzmann-Equation
  • Solvation Forces
  • Simulation Methods
  • Monte-Carlo-Methods
  • Molecular Dynamics Simulations
  • Proteinfolding

Learning Outcome

After successful participation in this module the student is able to:

  1. describe the bricks of life and to identify the chemical relation between them
  2. to describe quantitatively enzymatic processes
  3. identify and quantitatively describe pattern formation processes and to comprehend the underlying physcial mechanisms
  4. to describe membran potential and nerve action potential and to describe the underlying physical priniciples 
  5. to undertand and expalin photophysical process
  6. to understand and explain out of equilibirum thermodynamics concepts
  7. to describe and explain molecular forces in aqueous environment
  8. to understand the most prominent simulation and modelation methods
  9. develop a scientific theme with guidance, create a presentation and
    give a talk as well as judge presentation techniques and apply them.


no info

Courses, Learning and Teaching Methods and Literature

Courses and Schedule

VO 4 Biophysics Rief, M. Zacharias, M. Tue, 10:00–11:30, PH HS3
Tue, 12:30–14:00, PH HS3
Thu, 10:00–12:00, PH HS3
Thu, 14:00–16:00, PH HS3
UE 2 Exercise to Biophysics
Responsible/Coordination: Rief, M.
dates in groups eLearning

Learning and Teaching Methods

zuhören, arbeiten, lesen und lernen


Lecture with Seminar


  • Alberts et al. : Molecular Biology of the Cell
  • Nelson: Biological Physics
  • Lodish et al: Molecular Cell Biology
  • Stryer: Biochemistry
  • Jones: Soft Condensed Matter
  • Israelachvili: Intermolecular & Surface Forces
  • Hiemenz: Principles of colloid and surface chemistry
  • Sackmann and Merkel: Lehrbuch der Biophysik

Module Exam

Description of exams and course work

There will be an oral exam of 40 minutes duration. Therein the achievement of the competencies given in section learning outcome is tested exemplarily at least to the given cognition level using comprehension questions and sample calculations.

For example an assignment in the exam might be:

  • What are typical diffusion times in prokaryontic cells?
  • Describe quantenmechanical simulation techniques and discuss the limitations.
  • What are typical interaction energies in electrolyte solutions between proteins?
  • What are the structural elements of proteins?

Exam Repetition

The exam may be repeated at the end of the semester.

Current exam dates

Currently TUMonline lists the following exam dates. In addition to the general information above please refer to the current information given during the course.

Exam to Biophysics
Mon, 2024-02-12 till 23:55 Dummy-Termin. Die individuellen Termine werden nach Abschluss der Anmeldung durch das Dekanat festgelegt und werden in der vorlesungsfreien Zeit (Februar-April) stattfinden. till 2024-02-04
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