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In vitro Diagnostics (In vitro Diagnostics)

Module EI71032

This Module is offered by TUM Department of Electrical and Computer Engineering.

This module handbook serves to describe contents, learning outcome, methods and examination type as well as linking to current dates for courses and module examination in the respective sections.

Basic Information

EI71032 is a semester module in German or English language at Master’s level which is offered every semester.

This Module is included in the following catalogues within the study programs in physics.

  • Focus Area Bio-Sensors in M.Sc. Biomedical Engineering and Medical Physics
Total workloadContact hoursCredits (ECTS)
150 h 45 h 5 CP

Content, Learning Outcome and Preconditions


basics of in vitro diagnostics (role in the health care system, evaluation of test performance, admission and regulatory affairs, automation and throughput, handling of health-related personal data)
sample materials: Preparation, preanalytics;
immunoassays, antibodies and antibody - analoga;
basics of cellular immunobiology and tumor biology;
selected methods of molecular biology, molecular diagnostics and biomarkers;
cell analytics with optical and electrochemical methods; Flow Cytometry;
methods of cell separation: acoustophoresis, magnetophoresis;
digital holographic microscopy;
basics of statistical data evaluation;

Learning Outcome

After attending the course the students are able to
• apply the basic concepts and figures of merit in the field of in vitro diagnostics correctly,
• characterise the most important analytical (i.e. physical, chemical and biological) principles of in vitro diagnostics (both established and in a stage of research and development),
• interpret and evaluate the obtained data with regard to their statistical power, precision and medical information,
• analyse, evaluate and present given case studies and approaches for in vitro diagnostic solutions from current published research


Basic knowledge of biology and biochemistry

Courses, Learning and Teaching Methods and Literature

Courses and Schedule

VO 2 In vitro Diagnostics Thu, 09:45–11:15
UE 1 In vitro Diagnostics Thu, 11:15–12:00

Learning and Teaching Methods

The module is composed of a lecture (2 SWS) and an exercise (1 SWS).
The contents of the lecture will be communicated by talks. In the exercise students are encouraged to a self-reliant examination of scientific literature and to an immersion into selected topics of the field. The appropriate teaching format is individual and group work, case studies and presentation.


Presentations, writing board, experimental demonstration, videos;


The following reading material is recommended:
Klinische Chemie und Hämatologie. Klaus Dörner (Hrsg). Thieme Verlag, 8. Auflage 2013;
Further reading material will be provided by moodle in advance.

Module Exam

Description of exams and course work

In a written 60 min exam the students prove by solving tasks and answering questions, that they are able to correctly interpret the relationship between differentiated pathological health conditions and diagnostic parameters and data and to structure and analyse the construction principles and development processes of diagnostic analytics. In the exam no auxiliary means are allowed.
In the exercise the students prove their ability to analyse and discuss selected, published methods and results to problems of in vitro diagnostics. This learning achievement will be demonstrated by a presentation about a case study or scientific paper examined in homework.
The final grading is composed of the following elements:
80% written exam / 20% presentation

Exam Repetition

There is a possibility to take the exam in the following semester.

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