Applied Microbiology and Metabolic Engineering
This Module is offered by Associate Professorship of Microbial Biotechnology (Prof. Blombach).
This module handbook serves to describe contents, learning outcome, methods and examination type as well as linking to current dates for courses and module examination in the respective
CS0007 is a semester module
in English language
at Master’s level
which is offered in winter semester.
This Module is included in the following catalogues within the study programs in physics.
- Catalogue of non-physics elective courses
|Total workload||Contact hours||Credits (ECTS)|
Relevant techniques of applied microbiology and metabolic engineering: - microbial metabolism (biosynthesis and degradation pathways) - industrial microbiology: production of alcohols, amino and organic acids, vitamins, antibiotics, enzymes, etc. - bioprocessing techniques - metabolic engineering strategies (e.g. optimization of precursor and cofactor availability) - quantitative biology
Upon successful completion of the module, students will be familiar with the principles and relevant methods and techniques of applied microbiology and metabolic engineering. The students have gained knowledge of microbial fermentation processes and are able to develop strategies for the manipulation of cellular metabolism for selected product classes. The students have learned how to quantitatively describe fermentation processes and calculate mass balances. After completing the practical course, students will be able to cultivate a production strain, optimize process parameters, analyze biomass, substrate and product concentrations, and create a carbon balance of the process.
Fundamentals of Microbiology and Molecular Biology from the Bachelor's courses
Courses and Schedule
Learning and Teaching Methods
The contents of the lectures are conveyed by a talk of the lecturer, based on ppt-presentations.The blackboard might additionally be used to explain more complex relationships. To a limited extent, this can be supplemented by self-study of the literature mentioned in the lecture. In the practical course the implementation of the theoretically learned knowledge takes place, thereby the students' laboratory skills are trained with regard to the development and optimization of fermentation processes.
Description of exams and course work
In order to check whether students have understood the principles and relevant methods and techniques of applied microbiology and metabolic engineering not only in theory, but can also apply them practically, two forms of examination are used. On the one hand, the students answer questions on fermentation strategies during a written exam (90 min) and prove that they have understood the correlations of microbial metabolism. On the other hand, by drawing up written protocols for the laboratory tests carried out, the students demonstrate that they can carry out a selected production process and describe it quantitatively (for each experiment about 5 pages of protocol / not graded course achievement). Allowed tools are calculators. Additional resources may be approved by the lecturer if required.
There is a possibility to take the exam in the following semester.