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Protein and Nucleic Acid Chemistry

Module CH3042

This Module is offered by TUM Department of Chemistry.

This module handbook serves to describe contents, learning outcome, methods and examination type as well as linking to current dates for courses and module examination in the respective sections.

Basic Information

CH3042 is a semester module in English language at Master’s level which is offered in summer semester.

This module description is valid from SS 2018 to WS 2020/1.

Total workloadContact hoursCredits (ECTS)
150 h 45 h 5 CP

Content, Learning Outcome and Preconditions


The content of the module deals with the chemistry of proteins and nucleic acids. Particular attention is paid to chemical and biochemical methods for the artificial modification of these biomolecules. Furthermore, the application of such biomolecules as tools for the study and manipulation of biological processes is explained. The module is aimed at students of organic chemistry, biochemistry and molecular biotechnology.

Learning Outcome

After passing the module, students are able to:
A) Recognizing various possibilities for the modification of proteins and nucleic acids and their applications in a biological context,
B) understanding the chemical and biochemical consequences of modifications and assessing the different reaction possibilities in the context in vivo - in vitro,
C) Critical analysis and assessment of current articles,
D) Questioning the learned approaches and application to new biological problems.


Preliminary knowledge at the level of a B.Sc. biochemistry, organic chemistry or bio-organics.

Courses, Learning and Teaching Methods and Literature

Learning and Teaching Methods

The module consists of a lecture with accompanying exercise. The contents of the lecture will be conveyed during the lecture and through presentations. By referring and discussing relevant current literature, students should be encouraged to study the literature and the content of the subject. In addition, exam-relevant exercises are discussed and discussed during the lecture.


Powerpoint, blackboard, exercises


Reviews and current research that will be discussed during the module will be announced by the lecturer.

Module Exam

Description of exams and course work

The final module examination consists of a written test (90 minutes), in which students have to remember what has been taught about reactions on proteins and nucleic acids and applications of modified proteins and nucleic acids without any tools, and were they are to apply this knowledge to new problem sets. Answering the questions requires own formulations as well as drawing and explaining chemical structures and reaction mechanisms.

Exam Repetition

There is a possibility to take the exam in the following semester.

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