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Tissue Engineering and Regenerative Medicine: Fundamentals and Applications

Course 0000000950 in WS 2022/3

General Data

Course Type lecture
Semester Weekly Hours 3 SWS
Organisational Unit Chair of Medical Materials and Implants (Prof. Mela)
Lecturers Salma Mansi
Petra Mela
Diana Rojas Gonzalez
Dates Wed, 14:00–17:00, MW 1250

Assignment to Modules

Further Information

Courses are together with exams the building blocks for modules. Please keep in mind that information on the contents, learning outcomes and, especially examination conditions are given on the module level only – see section "Assignment to Modules" above.

additional remarks Tissue engineering and regenerative medicine (TERM) is a fast-growing field that addresses some of the major healthcare challenges, which result from the human incapability to regenerate diseased or lost tissues and organs. The biofabrication of living tissues and organs can potentially solve issues such as donor shortage and increasing waiting lists for organ transplantation, the lack of devices able to grow with the pediatric patients and the unavailability of therapies for yet untreated diseased. Furthermore, bioengineered human tissues and organs can serve as models for disease modeling and drug testing, with the advantage of being more predictive of the human response than the animal models, and the additional potential benefit of reducing the number of animals required for preclinical testing. This course will provide the students with the fundamentals to understand how the convergence of different disciplines such as engineering, biology, material science and medicine can result in new therapeutical solutions and have transformative implications for the future health care. The course ‘Tissue Engineering and Regenerative Medicine’ will provide a general understanding of tissue growth and development as well as the tools and theoretical information necessary to design tissues and organs. Specifically, the following topics will be covered in this module (subjected to change): • Principles of tissue engineering • Scaffolds: materials and characterization • Scaffold design, biomimicry • Biofabrication technology • Cell source, isolation, growth, differentiation • Bioreactor technology (from microfluidics to whole organ bioreactors) • Mechanical loading and culture conditions • Tissue/organ design and development • Tissue analysis and characterization • Current applications (e.g. cardiovascular, bone, skin, neural, muscle tissue engineering etc) • Cell therapy • Regulatory and ethical considerations • Translational approaches to the clinical settings
Links TUMonline entry

Equivalent Courses (e. g. in other semesters)

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