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Advanced Microfluidics

Course 0000004495 in WS 2022/3

General Data

Course Type lecture with integrated exercises
Semester Weekly Hours 4 SWS
Organisational Unit Assistant Professorship of Control and Manipulation of Microscale Living Objects (Prof. Destgeer)
Lecturers Ghulam Destgeer
Mehmet Akif Sahin
Helen Werner
Dates Thu, 15:00–18:00

Assignment to Modules

Further Information

Courses are together with exams the building blocks for modules. Please keep in mind that information on the contents, learning outcomes and, especially examination conditions are given on the module level only – see section "Assignment to Modules" above.

additional remarks The course will start by briefly introducing the field of microfluidics and its importance in diagnostics, pharmaceutical, medicine, etc. We will succinctly discuss the benefits of going smaller (microscale) by highlighting the difference between laminar and turbulent flows. Important concepts in microfluidics, such as scaling laws, Brownian motion, capillary flow, flow resistance, pumping mechanisms, diffusive mixing, pressure drops, flow rates and velocities, channel designs and dimensions, interfacial tensions and instabilities, etc., will be revised briefly for the better understanding of subsequent topics. It is recommended but not compulsory to take the “BioMEMS and Microfluidics” course by Prof. Bernhard Wolfrum, where the above introductory topics are covered in detail. We will distinguish between the active (acoustofluidics, dielectrophoresis, magnetophoresis, optofluidics, etc.) and passive (hydrodynamics, inertial microfluidics, gravitational, pinch flow fractionation, etc.) microfluidic systems, and list their advantages and disadvantages. We will then proceed to discuss in detail major microfluidic techniques used to manipulate cells, particles, droplets, microorganisms, and fluids. We will learn how a combination of more than one technique, e.g., dielectrophoretic and gravitational forces, or pinched flow fractionation and optical forces, can be combined to realize a hybrid microfluidic system. Moreover, we will learn the mechanism of microfluidic droplet generation, single cell/molecule encapsulation and limitations imposed by Poison statistics. We will also discuss paper microfluidics, digital microfluidics, and microfluidics-based particle fabrication using continuous/stop flow lithography techniques. Moving along, we will discuss various applications, such as mixing, sorting, separation, concentration, patterning, encapsulation, etc., of these techniques mentioned above. Course topics: • Introduction to microfluidics • Important concepts in microfluidics • Active and passive microfluidics • Hybrid microfluidic systems • Droplet microfluidics • Digital microfluidics • Paper microfluidics • Centrifugal microfluidics • Microfluidic manufacturing • Applications of microfluidics
Links TUMonline entry

Equivalent Courses (e. g. in other semesters)

SS 2022 Advanced Microfluidics Destgeer, G. Sahin, M. Werner, H. Tue, 09:00–12:00
WS 2021/2 Advanced Microfluidics Sahin, M. Werner, H.
Responsible/Coordination: Destgeer, G.
Mon, 15:00–16:30, virtuell
Fri, 15:30–17:00
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