Prof. Dr. Franz Pfeiffer

Photo von Prof. Dr. Franz Pfeiffer.
Telefon
+49 89 289-12551
Raum
Physik I: 2093
E-Mail
franz.pfeiffer@tum.de
Links
Homepage
Visitenkarte in TUMonline
Arbeitsgruppe
Biomedizinische Physik
Funktion
Professur für Biomedizinische Physik

Lehrveranstaltungen und Termine

Ausgeschriebene Angebote für Abschlussarbeiten

Fabrication of Grating-Structures for X-Ray Phase-Contrast Imaging using X-Ray Lithography

X-ray phase-contrast radiography and computed tomography is a recently developed novel biomedical imaging method that allows for a better contrast in soft tissues. It has the potential to improve diagnosis of lung diseases and detection of tumor metastasis and is currently implemented in first clinical prototype systems. This master thesis focuses on the further development and characterisation of grating structures using x-ray lithography from the ANKA synchrotron in Karlsruhe.

The thesis will be carried out in collaboration with the Karlsruhe Institute of Technology and the candidate will spent most if his time in Karlsruhe.

geeignet als
  • Masterarbeit Physik der kondensierten Materie
  • Masterarbeit Kern-, Teilchen- und Astrophysik
  • Masterarbeit Biophysik
  • Masterarbeit Applied and Engineering Physics
Themensteller(in): Franz Pfeiffer
Monte Carlo-based scatter correction for spectral computed tomography

In spectral x-ray computed tomography (spectral CT), tomographic scans of an object are conducted with two or more different photon energy spectra. This can be realized with photon counting detectors, which are able to partially resolve the energy of the detected photons. And contrary to conventional CT, spectral CT allows to retrieve information about the energy-dependent x-ray attenuation of the sample. The goal of this thesis is to develop a Monte Carlo-based scattering simulation framework for spectral CT and validate it with experimental measurements. Finally, the simulation framework should be combined with an existing iterative reconstruction algorithm in order to improve the quantitative accuracy of spectral CT and eliminate image artifacts. Experience with one (or more) of the following programming languages is desirable:  Python, C/C++, OpenCL.

geeignet als
  • Masterarbeit Physik der kondensierten Materie
  • Masterarbeit Kern-, Teilchen- und Astrophysik
  • Masterarbeit Biophysik
  • Masterarbeit Applied and Engineering Physics
Themensteller(in): Franz Pfeiffer
Quantitative Phase-Contrast-Based Iodine Imaging

Simultaneous access to phase- and absorption-contrast in X-ray computed tomography is provided by a Talbot-Lau interferometer at a laboratory setup. The complementary information of these two signals can be used for material decomposition and improved image processing. The project is focussed to clinical applications, especially separation of iodine and blood in an interventional stroke setting. The proposed thesis includes sample preparation, development of appropriate phantoms and independent accomplishement of the measurements on the experimental side. Development of the decomposition code based on theoretical models is a further step of the master project. 

geeignet als
  • Masterarbeit Physik der kondensierten Materie
  • Masterarbeit Kern-, Teilchen- und Astrophysik
  • Masterarbeit Biophysik
  • Masterarbeit Applied and Engineering Physics
Themensteller(in): Franz Pfeiffer

Kondensierte Materie

Wenn Atome sich zusammen tun, wird es interessant: Grundlagenforschung an Festkörperelementen, Nanostrukturen und neuen Materialien mit überraschenden Eigenschaften treffen auf innovative Anwendungen.

Kern-, Teilchen-, Astrophysik

Ziel der Forschung ist das Verständnis unserer Welt auf subatomarem Niveau, von den Atomkernen im Zentrum der Atome bis hin zu den elementarsten Bausteinen unserer Welt.

Biophysik

Biologische Systeme, vom Protein bis hin zu lebenden Zellen und deren Verbänden, gehorchen physikalischen Prinzipien. Unser Forschungsbereich Biophysik ist deutschlandweit einer der größten Zusammenschlüsse in diesem Bereich.